{"id":5299,"date":"2014-12-21T12:00:00","date_gmt":"2014-12-21T12:00:00","guid":{"rendered":"http:\/\/inclentrust.org\/new\/?page_id=5299"},"modified":"2019-03-11T10:36:53","modified_gmt":"2019-03-11T05:06:53","slug":"anti-thyroid-peroxidase-antibody-in-vitiligo-a-prevalence-study","status":"publish","type":"page","link":"https:\/\/inclentrust.org\/inclen\/anti-thyroid-peroxidase-antibody-in-vitiligo-a-prevalence-study\/","title":{"rendered":"Brain to Society project"},"content":{"rendered":"

[vc_row][vc_column width=”5\/6″ col_title=” Brain-to-Society Diagnostic for Prevention of Childhood Obesity and its Chronic Diseases” heading_style=”sec-heading2″ font_color=”rgba(158,23,68,0.72)”][\/vc_column][vc_column width=”1\/6″][vc_button title=”Back to List” target=”_self” color=”btn-primary” icon=”none” size=”wpb_regularsize” href=”https:\/\/inclentrust.org\/inclen\/?page_id=1669″][\/vc_column][\/vc_row][vc_row][vc_column width=”3\/4″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n
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  • Objectives<\/strong><\/li>\n<\/ul>\n

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    1. To examine the behavioral, body fatness\/weight and nutritional risk for childhood obesity and associated complications (MetS, T2D, and CVD) at baseline and 2-year follow-up changes in the sentinel sample that is exposed to multi-level Whole-of-Society transformation (i.e., PAG and WHA resolution for Quebec sample; IUI and WHA resolution in India). (Individual-level BtS Diagnostic)<\/u><\/em><\/li>\n
    2. To examine the direct impact of individual differences in genetic and neuro-cognitive predisposition for responsiveness to lifestyle-shaping environmental exposure conditions (i.e., endophenotype for environment responsiveness) on behavioral, body fatness\/weight and nutritional risk for childhood obesity (MetS, T2D, and CVD) and their moderating role on contextual differences in such environmental exposure conditions. (Individual-level BtS Diagnostic)<\/u><\/em><\/li>\n
    3. To proceed to foundational (qualitative and quantitative) work for subsequent computational systems science modelling (systems dynamic) of the relationships between aggregate-level measures of lifestyle-shaping environmental exposure conditions prevailing in communities (where sentinel samples live) and the organizational and collective choices made by community-level stakeholders (including health, social, and economic inputs, processes, outcomes and underlying mechanisms and feedbacks) involved in focal WoS interventions in Canada (PAG) and India (IUI). (Societal-level BtS Diagnostic) <\/u><\/em><\/li>\n
    4. To proceed to foundational work for subsequent computational systems science modelling (systems dynamic) of the relationships between aggregate-level measures of the caloric and nutritional quality of food supply, demand and consumption, and changes in agriculture and food systems practices, strategies and policies in relation to both the national WoS transformation in Canada (PAG) and India (IUI), as well as in the global WHA resolution A63\/12 (recommendations on the marketing of foods and non-alcoholic beverage to children). (Societal-level BtS Diagnostic)<\/u><\/em><\/li>\n<\/ol>\n<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
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  • Timeline\u00a0<\/strong><\/li>\n<\/ul>\n

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2011 \u2013 2016<\/td>\n<\/tr>\n
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  • Location<\/strong><\/li>\n<\/ul>\n

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India: <\/strong>Palwal, Haryana (with four sub-divisions: Palwal, Hodal, Hasanpur and Hathin) \u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Total Nine (9) villages divided into 3 clusters are selected for the study<\/p>\n

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  1. \n
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    1. Cluster 1 villages: Ratipur, Durgapur, Jodhpur<\/li>\n
    2. Cluster 2 villages: Sarai, Khatela, Nangla Eshanpur<\/li>\n
    3. Cluster 3 villages: Bahin, Kot, Pahari<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n

      Canada: <\/strong>Montreal, Quebec Province<\/p>\n<\/td>\n<\/tr>\n

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  • Methods<\/strong><\/li>\n<\/ul>\n

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Study Design: <\/strong>Longitudinal \/ Cohort Study<\/p>\n

Study population: <\/strong>612 Indian children and 612 Canadian children of 6-12 years of age distributed equally gender wise into 6 one year age bands i.e 17 males and 17 females in each age band from every cluster. These children are being recruited from 9 villages in India and 9 urban clusters in Canada.<\/p>\n

Follow up: <\/strong>for 2 years<\/td>\n<\/tr>\n

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  • Expected Outcomes<\/strong><\/li>\n<\/ul>\n

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Individual centered diagnostic<\/strong><\/p>\n
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  1. Primary outcomes: \u00a0<\/strong>\n
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    1. Change in food related behavior \u2013 dietary intake<\/li>\n
    2. Change in body weight & fatness – anthropometry<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n
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      1. Secondary outcomes:<\/strong>\n
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        1. Change in Nutritional risk for childhood obesity and associated complications – Biological risk markers \u2013 Heart rate, blood pressure, lipid profile, fasting insulin, glucose, HbA1c, hs-CRP<\/li>\n
        2. Change in proximal environmental exposures \u2013 Household environment, social network, education, built environment and physical activity status<\/li>\n
        3. Biologic exposure \u2013 genetic predisposition, neuro-cognitive predisposition, eating pattern phenotype<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n
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          1. Societal Level Diagnostic \u2013 <\/strong>\n
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            1. Change in Health promoting \/ hindering opportunities and constraints existing at aggregate level<\/li>\n
            2. Change in aggregate community specific responses \u2013 Food demand, purchase, consumption; mobility patterns & opportunities, Health & Economic outcomes; Psycho-social status<\/li>\n
            3. Aggregate change in society system \u2013 Agriculture; food system & supply chain; Marketing including influences of local communities; Media & communication policy changes; NGOs & other stakeholders<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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              Principal Investigator<\/strong><\/span><\/td>\n<\/tr>\n
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              • Dr. N. K Arora<\/li>\n
              • Prof. Laurette Dube<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
              Co-PI’s<\/strong><\/span><\/td>\n<\/tr>\n
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              • \u2022 Anoop Mishra<\/li>\n
              • \u2022 Atiqur Rahman<\/li>\n
              • \u2022 A Laxmaiah<\/li>\n
              • \u2022 Nikhil Tandon<\/li>\n
              • \u2022 Naval K. Vikram<\/li>\n
              • \u2022 K N Saraswathy<\/li>\n
              • \u2022 Jaishri Jethwaney<\/li>\n
              • \u2022 Manju Mehta<\/li>\n
              • \u2022 Ravindra M Pandey<\/li>\n
              • \u2022 Tanuja Aggarwala<\/li>\n
              • \u2022 Umesh Kapil<\/li>\n
              • \u2022 Anuja Agarwal<\/li>\n
              • \u2022 K. Mallikarjuna Rao<\/li>\n
              • \u2022 Manoja Kumar Das<\/li>\n
              • \u2022 Sonika Verma<\/li>\n
              • \u2022 Spencer Moore<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
              Implementation Team<\/strong><\/span><\/td>\n<\/tr>\n
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              • Sonika Verma<\/li>\n
              • Neha Gupta<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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                <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

                [vc_row][vc_column width=”5\/6″ col_title=” Brain-to-Society Diagnostic for Prevention of Childhood Obesity and its Chronic Diseases” heading_style=”sec-heading2″ font_color=”rgba(158,23,68,0.72)”][\/vc_column][vc_column width=”1\/6″][vc_button title=”Back to List” target=”_self” color=”btn-primary” icon=”none” size=”wpb_regularsize” href=”https:\/\/inclentrust.org\/inclen\/?page_id=1669″][\/vc_column][\/vc_row][vc_row][vc_column width=”3\/4″][vc_column_text] Objectives   To examine the behavioral, body fatness\/weight and nutritional risk for childhood obesity and associated complications (MetS, T2D, and CVD) at baseline and 2-year follow-up changes in the<\/p>\n

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